04/04/66 – 06/09/78 High School and College in Bochum, Germany
10/01/78 – 04/19/85 Study of medicine including internship at the Universities of Bochum, Cologne and Göttingen, Germany
04/30/85 License to practice medicine in Germany
05/10/85 M.D. degree awarded at the University of Göttingen
Post-Graduate Training:
06/01/85 – 05/30/87 Postdoctoral fellowship in electron microscopy, Department of Ophthalmology, University of Bonn, FRG
06/01/87 – 05/30/88 Residency training in ophthalmology, Department of Ophthalmology, University of Bonn, FRG
06/01/88 – 06/30/89 Research fellowship in immunohistochemistry and cell culture, Department of Pathology, Free University of Berlin, FRG
07/01/89 – 12/31/89 Residency training in Dermatology, Department of Dermatology, Klinikum Elberfeld, Wuppertal, Medical School University of Düsseldorf, FRG
07/01/90 – 04/30/91 Continued Residency training in Dermatology, Department of Dermatology, Klinikum Elberfeld, Wuppertal, Medical School University of Düsseldorf, FRG
05/01/94 – 06/30/95 Continued Residency training in Dermatology, Department of Dermatology, Klinikum Elberfeld, Wuppertal, Medical School University of Düsseldorf, FRG
01/01/90 – 06/30/90 Fellowship in Dermatopathology, Division of Dermatopathology, Department of Dermatology, New York University Medical Center
05/01/91 – 04/30/94 Research fellowship in molecular dermatology, Department of Cell Biology, Baylor College of Medicine, Houston, Texas
07/01/96 – 06/30/97 Internship in general pediatrics at Children’s Hospital of Michigan, Wayne State University, Detroit, Michigan
11/09/98 – 06/30/01 Residency in anatomic pathology at the Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
07/01/01 – 06/30/02 Fellowship in dermatopathology at the Section of Dermatology, The University of Chicago Hospitals, Chicago, Illinois
07/01/04 – 06/30/07 Residency in dermatology at the Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio
04/04/66 – 06/09/78 High School and College in Bochum, Germany
10/01/78 – 04/19/85 Study of medicine including internship at the Universities of Bochum, Cologne and Göttingen, Germany
04/30/85 License to practice medicine in Germany
05/10/85 M.D. degree awarded at the University of Göttingen
Post-Graduate Training:
06/01/85 – 05/30/87 Postdoctoral fellowship in electron microscopy, Department of Ophthalmology, University of Bonn, FRG
06/01/87 – 05/30/88 Residency training in ophthalmology, Department of Ophthalmology, University of Bonn, FRG
06/01/88 – 06/30/89 Research fellowship in immunohistochemistry and cell culture, Department of Pathology, Free University of Berlin, FRG
07/01/89 – 12/31/89 Residency training in Dermatology, Department of Dermatology, Klinikum Elberfeld, Wuppertal, Medical School University of Düsseldorf, FRG
07/01/90 – 04/30/91 Continued Residency training in Dermatology, Department of Dermatology, Klinikum Elberfeld, Wuppertal, Medical School University of Düsseldorf, FRG
05/01/94 – 06/30/95 Continued Residency training in Dermatology, Department of Dermatology, Klinikum Elberfeld, Wuppertal, Medical School University of Düsseldorf, FRG
01/01/90 – 06/30/90 Fellowship in Dermatopathology, Division of Dermatopathology, Department of Dermatology, New York University Medical Center
05/01/91 – 04/30/94 Research fellowship in molecular dermatology, Department of Cell Biology, Baylor College of Medicine, Houston, Texas
07/01/96 – 06/30/97 Internship in general pediatrics at Children’s Hospital of Michigan, Wayne State University, Detroit, Michigan
11/09/98 – 06/30/01 Residency in anatomic pathology at the Department of Pathology, Albert Einstein College of Medicine, Bronx, New York
07/01/01 – 06/30/02 Fellowship in dermatopathology at the Section of Dermatology, The University of Chicago Hospitals, Chicago, Illinois
07/01/04 – 06/30/07 Residency in dermatology at the Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio
10/12/2007 Dermatology, American Board of Dermatology
11/08/2002 Dermatopathology, American Board of Pathology
09/21/2001 Anatomic Pathology, American Board of Pathology
10/11/2001 Pathology, European Board of Pathology
08/31/1995 Dermatology, Ärztekammer Nordrhein Germany
LICENSES:
09/05/2000 Indiana 01052941A
05/22/2002 Florida ME85014
08/08/2008 Georgia 061517
06/06/2011 Arizona 44893
08/03/2011 California C 54810
01/21/2014 Tennessee 50841
06/18/2015 Michigan 4301068006
02/22/2016 North Carolina 2009-00315
2015-2016 Dermatologist and Dermatopathologist, Skin Cancer and Cosmetic Dermatology Treatment Center, Chattanooga, TN
2014-2015 Dermatologist and Dermatopathologist, Southside Dermatology, Jacksonville, FL
2008-2014 Dermatologist and Dermatopathologist, Nelson Dermatopathology Associates, Atlanta, GA
1978 First Prize in the German “Youth Research Competition”. Endocrinology of reproduction in pond snails
1980 First Prize in the “Philips European Competition for Young Researchers and Inventors”. Continued study on the endocrinology of reproduction in pond snails
Since 2010 International Society of Dermatopathology
Since 2008 Atlanta Dermatological Association
Since 2004 American Academy of Dermatology
Since 2003 American Society for Dermatopathology
2004-2007 Cleveland Dermatological Society
Clinical Professor of Dermatology
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
03/10/2011 – present
Adjunct Staff Member
Cleveland Clinic Foundation, Department of Dermatology, Cleveland, OH
01/01/2009 – present
Associate Professor of Dermatology and Pathology
University of Alabama at Birmingham, Department of Dermatology, Birmingham, AL
10/01/2007 – 10/31/2008
Clinical Associate
Cleveland Clinic Foundation, Division of Anatomic Pathology (Dermatopathology)
07/01/2003 – 06/30/2004
Assistant Professor of Pathology
Thomas Jefferson University, Department of Pathology, Cell Biology, and Anatomy, Philadelphia, PA
07/01/2002 – 06/30/2003
Curriculum/Course Development
Introduction to dermatopathology, University of Alabama at Birmingham Medical School (20 hours)
Trainees and Mentees
Colleen Embi, MD, 2003 – 2004, Cleveland Clinic private practice in dermatopathology
Lin Lin, MD, 2004 – 2005, Cleveland Clinic private practice in dermatopathology
Melissa Piliang, MD, 2005 – 2006, Cleveland Clinic Associate Staff in Dermatology, Cleveland Clinic
Rajiv Patel, MD, 2006 – 2007, Cleveland Clinic Associate Professor of Dermatology, University of Michigan, Ann Arbor
Dara Wakefield, MD, 2007 – 2008, University of Alabama at Birmingham Pathology Resident, University of Florida, Gainesville
Ibrahim Khalifeh, MD, 2008, University of Alabama at Birmingham Assistant Professor of Pathology, American University, Beirut, Lebanon
Teaching Material Produced
Core Curriculum in Dermatopathology, Medical School, University of Alabama at Birmingham, 01/01/2008
Teaching Administration
Fellowship Program Director, Dermatopathology, University of Alabama at Birmingham (2—10/31/2008)
Teaching Activities
2002-2004 Bimonthly dermatopathology teaching sessions on unknown cases, Department of Pathology, Thomas Jefferson University, Philadelphia, PA
2003-2007 Bimonthly dermatopathology teaching sessions on unknown cases, Section of Dermatopathology, Cleveland Clinic Foundation, Cleveland, OH
2003 & 2004, 2005 & 2006 Board preparation course in dermatopathology for dermatology residents in dermatopathology, Section of Dermatopathology, Cleveland Clinic Foundation, Cleveland, OH
2007-2008 Weekly dermatopathology teaching sessions on unknown cases, Department of Dermatology, University of Alabama at Birmingham
Since 2009 (biannually) Board preparation course in dermatopathology (whole day)
for dermatology residents, Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH
Reviewer
Journal of the American Academy of Dermatology
Experimental Dermatology
Pigment Cell Research
Journal of Cutaneous Pathology
American Journal of Dermatopathology
Archives of Dermatology
PLoS Medicine
Study Sections/Grant Review Committees
Skin Diseases Research Center, University of Alabama at Birmingham
Dates of Service: 01/01/2008 – 10/31/2008
1. European Club for Ophthalmic Fine Structure, Fourteenth Annual Meeting Oxford, England, 13/14th September 1986: Ultrastructure of the tunica vasculosa lentis posterior in the human embryo
2. International Seminar on Electron Microscopy Bonn, Germany, 10/11th January 1987: Ultrastructure of the tunica vasculosa lentis posterior in the human embryo
3. European Club for Ophthalmic Fine Structure, Fifteenth Annual Meeting Paris, France, 14/15th September 1987: Human scleral embryogenesis
4. European Club for Ophthalmic Fine Structure, Fifteenth Annual Meeting Paris, France, 14/15th September 1987: Fine structure of the developing human conjunctival epithelium
5. Seminar of the Rhenish Society for the Natural Sciences Bonn, Germany, 4th November 1987: Eye development during early gestation
6. Symposium of the Berlin Ophthalmological Society Berlin, Germany, 5/6th December 1987: Morphological observations on the prenatal development of the human eye
7. Symposium of the German Ophthalmological Society Berlin, Germany, 18th to 21st September 1988: Light and electron microscopical studies on the development of the human ciliary body
8. Symposium of the Rhenish-Westphalian Society for Dermatology Wuppertal, Germany, 27th to 29th October 1989: The developing human conjunctiva as a model for the embryogenesis of mucosal tissue
9. Symposium of the Wuppertal Society for Dermatology Wuppertal, Germany, 6th February 1991: Eosinophilic pustulosis Ofuji
10. Meeting of the Society for Investigative Dermatology Washington, D.C., USA, 10th to 12th September 1993: Inhibition of skin development by overexpression of transforming growth factor β1 in the epidermis of transgenic mice
11. Meeting of the United States and Canadian Academy of Pathology New Orleans, LA, USA, 25th to 31st March 2000: Expression and distribution of bcl-2 and and bax during the development of the human skin (platform)
12. 31st Annual Dermatopathology Self-Assessment Workshop The Cleveland Clinic Foundation, Cleveland, OH, USA, 4th October 2003 On Faculty – Case Presentation (cases 1 – 4)
13. 17th Annual Clinic Seminars Dermatology The Cleveland Clinic Foundation, Cleveland, OH, USA, 14th November 2003 On Faculty – What’s New in Dermatopathology? DNA microarrays: From structural genomics to functional genomics.
14. 32nd Annual Dermatopathology Self-Assessment Workshop The Cleveland Clinic Foundation, Cleveland, OH, USA, 9th October 2004 On Faculty – Case Presentation (cases 9 – 13)
15. 41st Annual Meeting of the American Society of Dermatopathology Boston, MA, USA, 14-17th October 2004 Is it appropriate for nondermatologists to perform skin biopsies?
16. 63rd Annual Meeting of the American Academy of Dermatology New Orleans, LA, USA, 18th – 22nd February 2005 Secondary syphilis presenting as cutaneous T cell lymphoma in an HIV-1 positive patient
17. 63rd Annual Meeting of the American Academy of Dermatology New Orleans, LA, USA, 18th – 22nd February 2005 Is it appropriate for nondermatologists to perform skin biopsies?
18. 63rd Annual Meeting of the American Academy of Dermatology New Orleans, LA, USA, 18th – 22nd February 2005 Evaluation of margins in melanocytic lesions – a survey of 152 dermatopathologists.
19. 63rd Annual Meeting of the American Academy of Dermatology San Francisco, CA, USA, 18th – 22nd February 2005 Targetoid lesions in biopsy-proven bullous pemphigoid.
20. 44th Annual Meeting of the American Society of Dermatopathology Baltimore, MD, USA, 14-17th October 2007 Dirofilaria repens presenting as a subcutaneous nodule.
21. 45th Annual Meeting of the American Society of Dermatopathology San Francisco, CA, USA, 16-19th October 2008 p16 Expression differentiates between desmoplastic melanoma and desmoplastic Spitz nevus.
22. 45th Annual Meeting of the American Society of Dermatopathology San Francisco, CA, USA, 16-19th October 2008 p16 Expression in trichilemmomas.
23. 45th Annual Meeting of the American Society of Dermatopathology San Francisco, CA, USA, 16-19th October 2008 Primary cutaneous carcinosarcoma mistaken for basal cell carcinoma.
24. 67rd Annual Meeting of the American Academy of Dermatology San Francisco, CA, USA, 6th –10th March 2009 Disseminated Fusarium in a neutropenic patient originating from toenail paronychia
25. 46th Annual Meeting of the American Society of Dermatopathology Chicago, IL, USA, 1-4th October 2009 Dermatofibrosarcoma protuberans: a tumor of nestin-positive cutaneous mesenchymal stem cells?
1. Whitehead, D. L., Sellheyer, K. (1982). The identification of ecdysterone (20-hydroxyecdysterone) in 3 species of molluscs (Gastropoda: Pulmonata). Experientia 38:1249-1251
2. Sellheyer, K., Spitznas, M. (1987) Ultrastructure of the human posterior tunica vasculosa lentis during early gestation. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:377-383
3. Sellheyer, K., Spitznas, M. (1988) The fine structure of the developing human choriocapillaris during the first trimester. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:65-74
4. Sellheyer, K., Spitznas, M. (1988) Surface morphology of the human ciliary body during prenatal development. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:78-83
5. Sellheyer, K., Spitznas, M. (1988) Development of the human sclera. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:89-100
6. Sellheyer, K., Spitznas, M. (1988) Differentiation of the human ciliary muscle in the embryo and fetus. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:281-287
7. Sellheyer, K., Spitznas, M. (1988) Morphology of the developing choroidal vasculature in the human fetus. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:461-467
8. Sellheyer, K., Spitznas, M. (1988) Surface differentiation of the human corneal epithelium during prenatal development. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:482-488
9. Sellheyer, K., Spitznas, M. (1988) Ultrastructural observations on the development of the human conjunctival epithelium. Graefe’s Arch. Clin. Exp. Ophthalmol. 226:489-499
10. Sellheyer, K. (1988) Pränatalentwicklung des menschlichen Auges. Teil 1. Ztschr. Prakt. Augenheilkde 9:191-197
11. Sellheyer, K. (1988) Pränatalentwicklung des menschlichen Auges. Teil 2. Ztschr. Prakt. Augenheilkde 9:307-310
12. Sellheyer, K., Spitznas, M. (1989) Licht- und elektronenmikroskopische Untersuchungen zur Entwicklung des menschlichen Ziliarkörpers. Fortschr. Ophthalmol. 86: 392-398
13. Sellheyer, K., Schwarting, R., Stein, H. (1989) Isolation and antigenic profile of follicular dendritic cells. Clin. Exp. Immunol. 78:431-436
14. Sellheyer, K. (1990) Morphology of the choroid and related structures during prenatal development. Eye 4:255-261
15. Sellheyer, K., Bickenbach, J.R., Rothnagel, J.A., Bundman, D., Longley, M.A., Krieg, T., Roche, N.S., Roberts, A.B., Roop, D.R. (1993) Inhibition of skin development by overexpression of transforming growth factor β 1 in the epidermis of transgenic mice. Proc. Natl. Acad. Sci. USA 90:5237-5241
16. Dominey, A.M., Wang, X.J., Gagne, T.A., Sellheyer, K., Bundman, D.S., Longley, M.A., Rothnagel, J.A., Greenhalgh, D.A., Roop, D.R. (1993) Targeted overexpression of transforming growth factor α in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differentiation 4:1071-1082
17. Rothnagel, J.A., Greenhalgh, D.A., Wang, X.-J., Sellheyer, K., Bickenbach, J.R., Dominey, A.M., Roop, D.R. (1993) Transgenic models of skin diseases. Arch. Dermatol. 129:1430-1436
18. Sellheyer, K. (1995) Transgenic mice as models for skin diseases. Hautarzt 46:755-761
19. Matzuk, M.M., Lu, N., Vogel, H., Sellheyer, K., Roop, D.R., Bradley, A. (1995) Multiple defects and perinatal death in mice deficient in follistatin.Nature 374:360-363
20. Sellheyer, K., Krahl, D., Ratech, H. (2001) Distribution of bcl-2 and bax in embryonic and fetal human skin: antiapoptotic and proapoptotic proteins are differentially expressed in developing skin. Am. J. Dermatopathol. 23:1-7
21. Sellheyer, K. (2003) Pathogenesis of solar elastosis: synthesis or degradation? J. Cutan. Pathol. 30:123-127
22. Sellheyer, K., Smoller, B.R. (2003) Dermatofibroma: upregulation of syndecan-1 expression in mesenchymal tissue. Am. J. Dermatopathol. 25:392-398
23. Sellheyer K, Soltani K, Shea CR. (2003) Pathologic quiz case: an enlarging, firm nodule on the abdominal skin in an otherwise healthy 73-year-old woman. Arch Pathol Lab Med. 127:E109-10
24. Sellheyer, K., Stein, S., Medenica, M. (2004) Vesicular eruption on the trunk and in intertriginous folds–quiz case. Arch Dermatol. 140: 231-236
25. Sellheyer, K., Belbin TJ (2004) DNA microarrays: From structural genomics to functional genomics – The applications of gene chips in dermatology and dermatopathology. J. Am. Acad. Dermatol. 51: 681-692
26. K. Chung, B.J., Embi, C.S., Sellheyer, K., Krakovitz P.R. (2005) Nasal juvenile xanthogranuloma. Arch. Otolaryngol. Head Neck Surg. 131: 81-82
27. Sellheyer, K., Bergfeld, W.F., E. Stewart, G. Roberson, J. Hammel (2005) Evaluation of surgical margins in melanocytic lesions: a survey among 152 dermatopathologists. J. Cutan. Pathol. 32:293-299
28. Sellheyer, K., Bergfeld, W.F. (2005) A retrospective biopsy study of the clinical diagnostic accuracy of common skin diseases by different specialties compared with dermatology. J. Am. Acad. Dermatol. 52:823-830
29. Sellheyer, K., Bergfeld, W.F. (2005) “Lesion,” “rule out…,” and other vagaries of filling out pathology requisition forms. J. Am. Acad. Dermatol. 52:914-915
30. Sellheyer, K., Bergfeld, W.F. (2005) When to ask your dermatopathologist to evaluate for surgical margins and when not: a matter of confusion for dermatologists and dermatopathologists alike. J. Am. Acad. Dermatol. 52:1095-1097
31. Sellheyer, K., Krahl, D. (2005) “Hidradenitis suppurativa” is Acne inversa! An appeal to (finally) abandon a misnomer. Int. J. Dermatol. 44:535-540
32. Sellheyer, K., Bergfeld, W.F. (2005) Differences in biopsy techniques of actinic keratoses by plastic surgeons and dermatologists: A histologically controlled pilot study. Arch Dermatol. 142:455-459
33. Sellheyer, K., Bergfeld, W.F. (2006) Histopathological evaluation of alopecias. Am. J. Dermatopathol. 28:236-259
34. Sellheyer, K., Krahl D. (2007) Response to letter to the editor regarding Hidradenitis suppurativa is acne inversa. Int J Dermatol. 46:330-332
35. Sellheyer, K., (2007) Mechanisms of laser hair removal: could persistent photoepilation induce vitiligo or defects in wound repair? Derm. Surg. 33:1055-1065
36. Krahl, D., Sellheyer, K. (2007) Monoclonal antibody Ber-EP4 reliably discriminates between microcystic adnexal carcinoma and basal cell carcinoma. J. Cutan. Pathol. 34:782-787
37. Sellheyer, K. Krahl, D., (2008) Basal cell (trichoblastic) carcinoma. Common expression pattern for epithelial cell adhesion molecule (Ep-CAM) links basal cell carcinoma to early follicular embryogenesis, secondary hair germ and outer root sheath of the vellus hair follicle: a clue to the adnexal nature of basal cell carcinoma? J. Am. Acad. Dermatol. 58:158-167
38. Sellheyer, K. Krahl, D., (2008) Ber-EP4 enhances the differential diagnostic accuracy of cytokeratin 7 in pagetoid cutaneous neoplasms. J. Cutan. Pathol. 35:366-372
39. Sellheyer, K. Krahl, D., (2008) What causes acne inversa (or hidradenitis suppurativa)? The debate continues. J. Cutan. Pathol. 35:701-703
40. Krahl, D., Sellheyer, K. (2009) A scanning microscopic clue to the diagnosis of arthropod assault reactions: alteration of interstitial tissue is more common than a wedge-shaped inflammatory infiltrate. J. Cutan. Pathol. 36:308-313
41. Hilliard, N.J., Wakefield, D.N., Krahl, D., Sellheyer, K. (2009) p16 Expression in conventional and desmoplastic trichilemmomas. Am. J. Dermatopathol. 31:342-349
42. Kwon EJ, Kristjansson AK, Meyerson HJ, Fedele GM, Tung RC, Sellheyer K, Tuthill RJ, Honda KS, Gilliam AC, McNiff JM. (2009) A case report of recurrent pseudolymphomatous folliculits – A mimic of cutaneous lymphoma. J. Am. Acad. Dermatol. 60:994-1000
43. Hilliard, N.J., Krahl, D., Sellheyer, K. (2009) p16 Expression differentiates between desmoplastic Spitz nevus and desmoplastic melanoma. J. Cutan. Pathol. 36:753-759
44. Khalifeh, I., Hughey, L.C., Huang, C.C., Reddy, V.V.B., Sellheyer, K. (2009) Solitary plaque on the scalp as a primary manifestation of Hodgkin lymphoma: a case report and review of the literature. J. Cutan. Pathol. 36 Suppl 1:80-85
45. Wakefield D.N., Krahl, D., Wainer B., Sellheyer, K. (2009) Cytologic atypia does not equal malignancy. A comparative analysis of melanocytic and neural lesions. J. Cutan. Pathol. 36:1014-1021
46. Krahl, D., Sellheyer, K. (2009) The neuroepithelial stem cell protein nestin is a marker of the companion cell layer of the adult and developing human hair follicle. Br. J. Dermatol. 161:678-682
47. Sellheyer, K., Nelson, P., Krahl, D., (2009) Dermatofibrosarcoma protuberans: a tumor of nestin-positive cutaneous mesenchymal stem cells? Br. J. Dermatol. 161:1317-1322
48. Krahl, D., Sellheyer, K., (2010) Sox9: more than a marker of the outer root sheath. Spatiotemporal expression pattern during human cutaneous embryogenesis. J. Cutan. Pathol. 37:350-356
49. Sellheyer, K., Krahl, D., (2010) Expression pattern of GATA-3 in embryonic and fetal human skin suggests a role in epidermal and follicular morphogenesis. J Cutan Pathol. 37:357-361
50. Sellheyer, K., Krahl, D., (2010) Blimp-1: a marker of terminal differentiation but not of sebocytic progenitor cells. A comparative analysis of embryonic and adult human skin with sebaceous neoplasms. J Cutan Pathol. 37:362-370
51. Sellheyer, K., Krahl, D., (2010) Mesenchymale Stammzellen der Haut. Gegenwärtiger Stand der Forschung, potenzielle klinische Anwendungen. Hautarzt 61:429-434
52. Bourgeois, G.P., Cafardi, J.A., Sellheyer, K., Andea A.A. (2010) Disseminated Fusarium in a neutropenic patient originating from toenail paronychia. Cutis 85:191-194
53. Sellheyer, K., Krahl, D., (2010) Cutaneous mesenchymal stem cells: Status of current knowledge, implications for dermatopathology. J. Cutan Pathol. 37:624-634
54. Sellheyer, K., Krahl, D., (2010) Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis and tumor stroma development. A study on embryonic and adult human skin. J. Am. Acad. Dermatol. 63:93-113
55. Krahl, D., Sellheyer, K., (2010) p75 Neurotrophin receptor differentiates between morphoeic basal cell carcinoma and desmoplastic trichoepithelioma: Insights into the histogenesis of adnexal tumours based on embryology and hair follicle biology. Br. J. Dermatol. 163:138-145
56. Sellheyer, K. (2010) Focusing on leaves while ignoring the forest: Reflections on the lack of hypothesis-driven research in dermatopathology and what is to be done J. Cutan Pathol. 37:328-321
57. Sellheyer, K., Krahl, D., (2010) Skin mesenchymal stem cells: prospects for clinical dermatology. J. Am. Acad. Dermatol. 63:859-865
58. Krahl, D., Sellheyer, K., (2010) Basal cell carcinoma and pilomatrixoma mirror human follicular embryogenesis as reflected by their differential expression patterns of SOX9 and beta-catenin. Br. J. Dermatol. 162: 1294-1301
59. Sellheyer, K., Nelson, P., Bergfeld, W.F. (2010) Inadequate biopsy technique and specimen size: an alarming trend that compromises patient care and an appeal to our clinical colleagues. Arch. Dermatol. 146:1180-1181
60. Sellheyer, K., (2011) Basal cell carcinoma and stem cell markers: contribution to possible histogenesis? Hautarzt 62:119-127
61. Sellheyer, K., Krahl, D. (2011) PHLDA1 (TDAG51) is a follicular stem cell marker and differentiates between morphoeic basal cell carcinoma and desmoplastic trichoepithelioma. Br. J. Dermatol. 164:141-147
62. Sellheyer, K., (2011) Basal cell carcinoma: cell of origin, cancer stem cell hypothesis, and stem cell markers. Br. J. Dermatol. 164:696-711
63. Sellheyer, K., Nelson, P., Patel, R.M. (2011) Expression of embryonic stem cell markers SOX2 and nestin in dermatofibrosarcoma protuberans and dermatofibroma. J. Cutan. Pathol. 38:415-419
64. Sellheyer, K., (2011) Stem cell markers can help identify adnexal tumor differentiation when evaluated in the context of morphology: methodology matters. J. Cutan. Pathol. 38:460-474
65. Sellheyer, K., Nelson, P. (2010) Follicular stem cell marker PHLDA1 (TDAG51) is superior to cytokeratin 20 in differentiating between trichoepithelioma and basal cell carcinoma in small biopsy specimens. J. Cutan. Pathol. 38:542-550
66. Sellheyer, K., Krahl, D. (2011) Does the peritumoral stroma of basal cell carcinoma recapitulate the follicular connective tissue sheath? A comparative analysis of nestin expression in basal cell carcinoma, trichoepithelioma, trichoblastoma, and the hair follicle. J. Cutan. Pathol. 38:551-559
67. Sellheyer, K., Atanaskova-Mesinkovska, N., Nelson, P., Bergfeld, W.F. (2011) Differential expression of stem cell markers in lichen planopilaris and alopecia areata. Br. J. Dermatol. 165:1149-1151
68. Sellheyer, K., Nelson, P. , Kutzner, H. (2012) Fibroepithelioma of Pinkus is a true basal cell carcinoma developing in association with a newly identified tumour-specific type of epidermal hyperplasia. Br. J. Dermatol. 166:88-97
69. Sellheyer, K. (2012) Reply: Methodology matters as does knowledge of underlying basic science…. J. Cutan. Pathol. 39:83-87
70. Sellheyer, K., Nelson, P. (2012) The ventral proximal nail fold: stem cell niche of the nail and equivalent to the follicular bulge. A study on developing human skin. J. Cutan. Pathol. 39:835-843
71. Sellheyer, K. (2013) Nail stem cells. J. Dtsch. Dermatol. Ges. 11:235-239
72. Sellheyer, K., Nelson P., Kutzner H., Patel R.M. (2013) The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers. J. Cutan. Pathol. 40:363-370
73. Sellheyer, K., Cribier, B., Nelson, P., Kutzner, H., Rütten, A (2013) Basaloid tumors in nevus sebaceus revisited: the follicular stem cell marker PHLDA1 (TDAG51) indicates that most are basal cell carcinomas and not trichoblastomas. J. Cutan Pathol. 40:455-462
74. Sellheyer, K., Nelson P. (2013) The concept of the onychodermis (specialized nail mesenchyme): an embryological assessment and a comparative analysis with the hair follicle. J. Cutan Pathol. 40:463-471
75. Sellheyer, K., Nelson, P. (2013) CD133, a stem cell marker in mice: results in animal models cannot always be applied to human skin. J. Cutan. Pathol. 40:690-692
76. Buster K.J., Burford H.N., Stewart F.A., Sellheyer K., Hughey L.C. (2013) Sclerema neonatorum treated with intravenous immunoglobulin: a case report and review of treatments. Cutis 92:83-87
77. Sellheyer, K., Nelson, P., Bergfeld, W.F. (2014) Nonspecific histopathological diagnoses: the impact of partial biopsy and the need for a consensus guideline. JAMA Dermatol. 150:11-12
78. Sellheyer, K. (2015) Spiradenoma and cylindroma originate from the hair follicle bulge and not from the eccrine sweat gland: an immunohistochemical study with CD200 and other stem cell markers. J. Cutan. Pathol. 42:90-101
M.D.
About Dr. Klaus Sellheyer
Dr. Klaus Sellheyer is board-certified in dermatology, anatomic pathology, and dermatopathology, and joined FLDSCC in 2016. He was born in Germany, where he obtained his Doctor of Medicine degree from the Georg-August-University, and completed a residency in dermatology. Dr. Sellheyer completed a research fellowship in immunohistochemistry and cell culture at the Free University of Berlin, one of Germany’s most distinguished universities. He also has conducted extensive research in eye disease and electron microscopy.
After immigrating to the United States in 1998, Dr. Sellheyer completed additional residency training in anatomic pathology at the Albert Einstein College of Medicine and in dermatology at the Cleveland Clinic Foundation. In addition, he undertook fellowship training in dermatopathology at New York University Medical Center and at the University of Chicago Hospitals. Dr. Sellheyer also trained for three years in molecular dermatology at Baylor College of Medicine. With his extensive training, Dr. Sellheyer has held many academic posts and professorships at medical schools across the country. He has authored more than 75 papers relating to diseases of the skin, and published in peer-reviewed journals and books.
At FLDSCC, Dr. Sellheyer focuses on dermatopathology and treats patients with various skin conditions.
In his spare time, Dr. Sellheyer likes to bike, travel, and listen to classical music.